In recent decades, the Information Technology and communication are incorporated in all areas extensively, and has also influenced in education, though still a journey for all of its implementation, as it is a process slowly and with great difficulty, since teachers are not yet confident in the process. Students are the key piece to check the integration of ICT in education, therefore, this article focuses on a systematic review of the literature on ICT skills of the university students, and for this set two areas: technological competence and pedagogical skills and the relationship between them, and in turn, using the same, and the influence of other dimensions. New forms of learning and teaching need a change in teaching methodologies and the role of teachers and students. The results provide clues to the changing educational policies, professional development, initial and ongoing training of teachers and the restructuring of the education system.