REASSORTANTS WITH EQUINE-1 (H7N7) INFLUENZA-VIRUS HEMAGGLUTININ IN AN AVIAN INFLUENZA-VIRUS GENETIC BACKGROUND ARE PATHOGENIC IN CHICKENS

被引：10

作者：

BANBURA, MW ^{[1
]}

KAWAOKA, Y ^{[1
]}

THOMAS, TL ^{[1
]}

WEBSTER, RG ^{[1
]}

机构：

[1] ST JUDE CHILDRENS RES HOSP, DEPT VIROL & MOLEC BIOL, 332 N LAUDERDALE, POB 318, MEMPHIS, TN 38101 USA

来源：

VIROLOGY | 1991年 / 184卷 / 01期

关键词：

D O I：

10.1016/0042-6822(91)90872-9

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Reassortants possessing the hemagglutinin (HA) gene from A/Equine/London/1416/73 (H7N7) [Eq/Lond] and five or more genes from A/Chicken/Pennsylvania/1370/83 (H5N2) [Ck/Penn] were lethal in chickens. This result demonstrates that horses can maintain influenza viruses whose HAs are capable of promoting virulence. Thus, reassortment of equine and avian influenza virus genes could generate viruses that might be lethal in domestic poultry. © 1991 Academic Press, Inc.

引用

页码：469 / 471

页数：3

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