PREPARATION OF 2-AZIDO-4-O-BENZOYL-2,6-DIDEOXY-3-O-METHYL-BETA-D-ALLOPYRANOSE AND ITS DISACCHARIDE DERIVATIVE

2-Azido-4-O-benzoyl-2,6-dideoxy-3-O-methyl-D-allopyranose, needed as one of the building blocks for construction of a novel cyclodextrin-like compound, was prepared in the form of crystalline beta-anomer 6 from methyl 2-azido-4,6-O-benzylidene-2-deoxy-alpha-D-allopyranoside 1. As a model of alpha-glycosidation necessary for formation of a cyclic structure, 6 was converted into the corresponding beta-glycosyl trichloroacetimidate and coupled with methyl 6-O-benzyl-2,3-di-O-methyl-alpha-D-glucopyranoside 8, giving alpha(1-->4)-linked disaccharide derivative 9.