EFFECTS OF HYPERBARISM ON CENTRAL RESPIRATORY DRIVE AND RESPIRATORY PATTERN IN HUMANS

被引:0
|
作者
ROCCO, M
PELAIA, P
CONTI, G
MALPIERI, R
COTTINI, F
BORTONE, C
GASPARETTO, A
机构
[1] UNIV ROMA LA SAPIENZA, RESP MED LAB, ROME, ITALY
[2] UNIV TRIESTE, INST ANAESTHESIA & INTENS CARE, TRIESTE, ITALY
关键词
HYPERBARIC AIR; RESPIRATORY DRIVE; RESPIRATORY PATTERN; INSPIRATORY OCCLUSION PRESSURE; IMPEDANCE OF THE RESPIRATORY SYSTEM;
D O I
暂无
中图分类号
Q17 [水生生物学];
学科分类号
071004 ;
摘要
The aim of our study was to evaluate the effects of increasing pressure (from 1 to 3 and 6 atm abs) on respiratory drive, respiratory pattern, and inspiratory impedance of the respiratory system. Seven healthy volunteers were studied during a dry compression to 6 atm abs in a hyperbaric multiplace chamber. We observed a significant increase in tidal volume, P-0.1 (the pressure generated in the airway after 100 ms of inspiration against a closed inspiratory line), T-tot, and T-i, and a significant respiratory rate reduction with increasing pressure from 1 to 3 atm.abs; P-0.1 also increased significantly when comparing 3 and 6 atm abs measurement with 1 atm abs. The P > 0.01 and P-0.1/(VT/T-i) showed a significant progressive increase compared with 1 atm abs. In conclusion, the passage from 1 to 3 and 6 atm abs causes, in healthy subjects at rest, an increase in the central respiratory drive activity, evaluated with P-0.1 measurement. The response to the respiration system is an increase in tidal volume and T-i with a decrease in respiratory rate.
引用
收藏
页码:315 / 319
页数:5
相关论文
共 50 条
  • [21] Impaired central respiratory drive in myotonic dystrophy
    Zifko, U
    Hahn, AF
    George, CFP
    Remtulla, H
    Bolton, CF
    ANNALS OF NEUROLOGY, 1996, 40 (03) : M86 - M86
  • [22] Central Respiratory Drive in Patients With Neuromuscular Diseases
    Rialp, Gemma
    Maria Raurich, Joan
    Antonio Llompart-Pou, Juan
    Ayestaran, Ignacio
    Ibanez, Jordi
    RESPIRATORY CARE, 2013, 58 (03) : 450 - 457
  • [23] EFFECTS OF ACUTE EXPOSURE TO HIGH-ALTITUDE ON VENTILATORY DRIVE AND RESPIRATORY PATTERN
    BURKI, NK
    JOURNAL OF APPLIED PHYSIOLOGY, 1984, 56 (04) : 1027 - 1031
  • [24] EFFECTS OF HELIUM BREATHING ON RESPIRATORY DRIVE
    DEWEESE, EL
    SULLIVAN, TY
    YU, PL
    CLINICAL RESEARCH, 1982, 30 (04): : A750 - A750
  • [25] RESPIRATORY DRIVE AND BREATHING PATTERN DURING EXERCISE IN MAN
    LIND, FG
    ACTA PHYSIOLOGICA SCANDINAVICA, 1984, : 1 - 47
  • [26] Bidirectional Plasticity of Pontine Pneumotaxic Postinspiratory Drive: Implication for a Pontomedullary Respiratory Central Pattern Generator
    Poon, Chi-Sang
    Song, Gang
    CENTRAL NERVOUS SYSTEM CONTROL OF RESPIRATION, 2014, 209 : 235 - 254
  • [27] EFFECTS OF MIDAZOLAM ON RESPIRATORY MUSCLES IN HUMANS
    MOLLIEX, S
    DUREUIL, B
    MONTRAVERS, P
    DESMONTS, JM
    ANESTHESIA AND ANALGESIA, 1993, 77 (03): : 592 - 597
  • [28] CENTRAL RESPIRATORY DRIVE AND HYPOXIC STIMULUS IN ACUTE VENTILATORY FAILURE OF CHRONIC RESPIRATORY PATIENTS
    AUBIER, M
    DERENNE, JP
    MURCIANO, D
    FOURNIER, M
    PARIENTE, R
    INTENSIVE CARE MEDICINE, 1977, 3 (03) : 112 - 112
  • [29] INFLUENCE OF THE RESPIRATORY ROUTE ON THE RESTING BREATHING PATTERN IN HUMANS
    RODENSTEIN, DO
    MERCENIER, C
    STANESCU, DC
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1985, 131 (01): : 163 - 166
  • [30] Review of central respiratory pattern generation models
    Butera, RJ
    SECOND JOINT EMBS-BMES CONFERENCE 2002, VOLS 1-3, CONFERENCE PROCEEDINGS: BIOENGINEERING - INTEGRATIVE METHODOLOGIES, NEW TECHNOLOGIES, 2002, : 1507 - 1508