USE OF NEBULIZED LIPOSOMAL AMPHOTERICIN-B IN THE TREATMENT OF ASPERGILLUS-FUMIGATUS EMPYEMA

被引：33
|
作者：
PURCELL, IF [1 ]
CORRIS, PA [1 ]
机构：
[1] FREEMAN RD HOSP,CTR CARDIOTHORAC,NEWCASTLE TYNE NE7 7DN,TYNE & WEAR,ENGLAND
来源：
THORAX | 1995年 / 50卷 / 12期
关键词：
ASPERGILLUS FUMIGATUS; EMPYEMA; LIPOSOMAL AMPHOTERICIN B; NEBULIZER;
D O I：
10.1136/thx.50.12.1321
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
A 28 year old man with asthma, broncho-pulmonary aspergillosis, pulmonary thromboembolic disease, and pulmonary hypertension developed Aspergillus fumigatus empyema complicating a pneumothorax. His condition progressively deteriorated despite treatment with intravenous and intrapleural amphotericin B, but improved promptly after substituting nebulised liposomal amphotericin B and oral itraconazole. This experience suggests that nebulised liposomal amphotericin B is well tolerated and merits further assessment in the treatment of pulmonary fungal disease.
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页码：1321 / 1323
页数：3
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