A NEW APPARATUS FOR THE DETERMINATION OF THE EMITTED DOSE FROM PRESSURIZED METERED-DOSE INHALATION AEROSOLS WITH INHALATION DEVICES

被引：2
|
作者：
GADDIPATI, N
GRAZIOSI, M
GANESAN, M
机构：
[1] Medical Research Division American Cyanamid Company, Pearl River, NY
来源：
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1995年 / 21卷 / 12期
关键词：
D O I：
10.3109/03639049509063028
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A new in vitro test apparatus is described in this report to test the emitted dose from the pressurized metered dose inhalation aerosols (MDI) with inhalation devices. Drug deposition from MDIs in conjunction with different inhalation chambers was studied using a new apparatus and compendial apparatuses. The new apparatus is simple and offers an alternate method to determine the small particle fraction delivered from MDI aerosols with inhalation devices.
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页码：1399 / 1409
页数：11
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