Insulin Resistance and Anthropometric Parameters Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is a frequently seen endocrine metabolic disorder in adult women Insulin resistance (IR), associated with 30-70%, PCOS cases, has also been reported to underly increased cardiovascular risk in PCOS together with hyperandrogenism and dislipidemia. The aim of our study was to measure the frequency of IR in patients with PCOS by comparing anthropometric parameters and evaluate the prevalence of the metabolic syndrome (MBS). Sixtyone adult women with PCOS (aged 25.34 +/- 6,19 years) were investigated along with fourty healty women (aged 27.8 +/- 4.99 years) recruited from the hospital staff as the control group. Glucose, insulin, C-peptide, total. cholesterol. triglycerides, HDL, LDL, LH, FSH, prolactin, eostradiol, total testosterone, free testosterone, DHEA-S values were measured. Anthropometric measurements were carried out and IR was calculated using the HOMA Formula. as the patient group IR and the anthropometric measurements of weight (p=0,000), BMI (P=0,000), waist circumference (P=0,002), hip crrcumference (P=0,000). arm circumference (P=0.000), neck circumference (P=0,015) were significantly different as compared to the conrol group values. A statistically significant difference, determined in accordance with the IDF criteria, existed between the PCOS and the control groups (p=0.03). with respect to incidence of MBS. The results suggested that PCOS is associated with IR. The anthropometric parameters measured were higher in PCOS as compared to the controls and MBS was apparent in 26% of the PCOS cases, We also concluded that obesity is an additonal risk factor in IR.