ANTISPASMODIC AND ANTHELMINTIC ACTIVITY OF NYCTANTHES ARBORTRISTIS LINN

被引：9
|
作者：
Das, Sanjita [1 ]
Sasmal, Dinakar [2 ]
Basu, Saumya Priya [1 ]
机构：
[1] Noida Inst Engn & Technol, Dept Pharmaceut Technol, Greater Noida, UP, India
[2] Birla Inst Technol, Dept Pharmaceut Sci, Ranchi, Jharkhand, India
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | 2010年 / 1卷 / 02期
关键词：
Nyctanthes arbortristis Linn; antispasmodic; Pheretima posthuma; anthelmintic activity; acetylcholine;
D O I：
10.13040/IJPSR.0975-8232.1(2).51-55
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Antispasmodic activity of the ethanolic extracts of different parts of Nyctanthes arbortristis Linn. was estimated using guinea pig ileum preparation against acetylcholine. Anthelmintic activity was tested following the method described by Kailashraj and Kurup, using earthworm (Pheretima posthuma). The extracts exhibited antispasmodic activity, which was less than that of piperazine citrate. The ethanolic extracts were found to have concentration-dependent paralytic activity, whereas its seeds and flowers showed lethal effect on the worms. It was also observed that the paralytic and lethal effects of respective ethanolic extracts were potentiated by the presence of atropine. It reveals that the anthelmintic activity of the extracts is due to the inhibition of motility by relaxing and depressing responsiveness to contractile action of acetylcholine.
引用
收藏
页码：51 / 55
页数：5
相关论文
共 50 条
  • [1] Diuretic activity of Nyctanthes arbortristis Linn.
    Sasmal, D.
    Das, Sanjita
    Basu, S. P.
    ANCIENT SCIENCE OF LIFE, 2007, 27 (02) : 19 - 23
  • [2] Chemical Constituent of Nyctanthes arbortristis Linn Leaf
    Rahman, Mohammad M.
    NATURAL PRODUCTS JOURNAL, 2013, 3 (01): : 71 - 76
  • [3] Antidiabetic Activity of Nyctanthes Arbortristis
    Nanu, Rathod
    Raghuveer, I
    Chitme, H. R.
    Chandra, Ramesh
    PHARMACOGNOSY MAGAZINE, 2008, 4 (16) : 335 - 340
  • [4] Antiasthmatic Activity of Nyctanthes arbortristis Leaves
    Nirmal, Sunil A.
    Pal, Subodh C.
    Mandal, Subhash C.
    LATIN AMERICAN JOURNAL OF PHARMACY, 2011, 30 (04): : 654 - 660
  • [5] Evaluation of CNS Depressant Activity of Different Plant parts of Nyctanthes arbortristis Linn.
    Das, Sanjita
    Sasmal, D.
    Basu, S. P.
    INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2008, 70 (06) : 803 - 806
  • [6] In vitro clonal propagation of Nyctanthes arbortristis Linn. -: a medicinal tree
    Rout, G. R.
    Mahato, A.
    Senapati, S. K.
    HORTICULTURAL SCIENCE, 2007, 34 (02) : 84 - 89
  • [7] Molecular Docking Studies on Phytoconstituent Isolated from Nyctanthes arbortristis Linn.
    Rajput, Devyani
    Jain, Dharmendra
    Kashaw, Sushil Kumar
    Patil, Umesh Kumar
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION, 2024, 14 (02) : 399 - 408
  • [8] STRUCTURE ELUCIDATION OF OLIGOSACCHARIDES FROM NYCTANTHES-ARBORTRISTIS LINN - SEEDS GLUCOMANNAN
    SINGH, RB
    JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1989, 66 (04) : 258 - 259
  • [9] Fuel potential and elemental composition of the shrub Seuli wood, Nyctanthes arbortristis Linn
    Rahman, M. M.
    Shahjahan, M.
    INTERNATIONAL WOOD PRODUCTS JOURNAL, 2012, 3 (02) : 89 - 95
  • [10] Arbortristoside-A: A Promising Bioactive Moiety from Nyctanthes arbortristis Linn. against Hemorrhoid
    Das, Sanjita
    Das, Saumya
    Singh, Aniruddh Pratap
    Das, Manas Kumar
    Gautam, Nishu
    Kumar, P. Ayash
    Mohapatra, Sradhanjali
    Shakya, Richa
    PHARMACOGNOSY MAGAZINE, 2021, 17 (76) : 695 - 699
12345