CHARACTERISTIC VISIBLE FLUORESCENCE EMISSION-SPECTRA OF SERA FROM CANCER-PATIENTS

被引:4
|
作者
AIKEN, JH
HUIE, CW
TERZIAN, JA
机构
[1] SUNY BINGHAMTON,DEPT CHEM,BINGHAMTON,NY 13902
[2] OUR LADY LOURDES HOSP,DEPT PATHOL,BINGHAMTON,NY 13905
关键词
CANCER DIAGNOSIS; PORPHYRIN FLUORESCENCE; VISIBLE FLUOROMETRY;
D O I
10.1080/00032719408001091
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The feasibility of using visible fluorimetry as a simple spectroscopic method for cancer diagnosis and/or management was investigated by recording the visible fluorescence emission spectra of sera from cancer patients and healthy individuals. Characteristic visible fluorescence emission spectra were found to occur in sera of some cancer patients, e.g., patients with breast or lung cancer, with spectral features similar to those observed among porphyrin and porphyrin-related compounds. Possible physico-chemical factors responsible for the occurrence of these unique visible fluorescence features among cancer patients were briefly discussed.
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页码:511 / 521
页数:11
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