INFLUENCE OF SOLID FRICTION ON POLYMER RELAXATION IN GEL-ELECTROPHORESIS

被引：33
|
作者：
BURLATSKY, S
DEUTCH, J
机构：
[1] Department of Chemistry, Massachusetts Institute of Technology, Cambridge
来源：
SCIENCE | 1993年 / 260卷 / 5115期
关键词：
D O I：
10.1126/science.260.5115.1782
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Solid friction between a charged polymer and fixed gel points can dramatically affect polymer mobility in gel electrophoresis. The effect is present when a polymer chain is entangled over many gel points along a portion of its length, leading to significantly different behavior than predicted by conventional theory: the mobility of the chain decreases and exhibits a stronger length dependence, which separates long linear charged polymers of different molecular weights.
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页码：1782 / 1784
页数：3
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