COMPARISON OF PROPOFOL AND THIOPENTONE AS ANESTHETIC AGENTS FOR ELECTROCONVULSIVE-THERAPY

被引：48

作者：

BOEY, WK ^{[1
]}

LAI, FO ^{[1
]}

机构：

[1] TOA PAYOH GEN HOSP, DEPT ANAESTHESIA, SINGAPORE 1129, SINGAPORE

来源：

ANAESTHESIA | 1990年 / 45卷 / 08期

关键词：

Anaesthetics; intravenous; thiopentone; propofol; Electroconvulsive therapy;

D O I：

10.1111/j.1365-2044.1990.tb14383.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Propofol and thiopentone were compared as anaesthetic agents for electroconvulsive therapy in 31 patients on four occasions in a repeated measure crossover study. Discomfort on injection was significantly more common with propofol (51.6% of anaesthetics) compared to thiopentone (1.6% of anaesthetics). The duration of seizure was shorter with propofol in both treatments but there was significant drug‐time interaction. Propofol gave a milder tonus and clonus during seizure when both treatments were considered together. The increase in systolic and diastolic arterial pressures and heart rate after treatment were significantly higher with thiopentone. Apnoea was significantly longer with propofol. The times to sitting up unaided and opening the eyes on command were the same for both drugs. The ability to walk 10 m 20 minutes after anaesthesia was significantly better with propofol (p < 0.0001). Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：623 / 628

页数：6

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