DNA ANEUPLOIDY IN ECTOPIC PREGNANCY AND SPONTANEOUS-ABORTIONS

被引:20
|
作者
TOIKKANEN, S
JOENSUU, H
ERKKOLA, R
机构
[1] UNIV CENT HOSP TURKU,DEPT ONCOL & RADIOTHERAPY,TURKU,FINLAND
[2] UNIV CENT HOSP TURKU,DEPT GYNECOL & OBSTET,TURKU,FINLAND
关键词
FLOW CYTOMETRY; ANEUPLOIDY; ECTOPIC PREGNANCY;
D O I
10.1016/0028-2243(93)90184-E
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The nuclear DNA content of 55 ectopic tubal pregnancies was studied by flow cytometry from paraffin embedded tissue blocks. An abnormal amount of DNA content was found in 24% of the cases. This was a significantly higher percentage than encountered in 92 spontaneous abortions studied by the same method in the same population (8%, P=0.01). The result indicates that, in addition to the maternal factors, abnormal embryogenesis with grave chromosomal aberrations may play a major role in the etiology of ectopic pregnancy.
引用
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页码:9 / 13
页数:5
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