OBSTETRICAL COMPLICATIONS IN PATIENTS WITH BIPOLAR DISORDER AND THEIR SIBLINGS

被引：56
|
作者：
KINNEY, DK [1 ]
YURGELUNTODD, DA [1 ]
LEVY, DL [1 ]
MEDOFF, D [1 ]
LAJONCHERE, CM [1 ]
RADFORDPAREGOL, M [1 ]
机构：
[1] HARVARD UNIV,SCH MED,DEPT PSYCHIAT,BOSTON,MA 02115
来源：
PSYCHIATRY RESEARCH | 1993年 / 48卷 / 01期
关键词：
AFFECTIVE DISORDER; PRENATAL AND PERINATAL COMPLICATIONS; MANIC DEPRESSIVE ILLNESS; MOOD DISORDERS; RISK FACTORS;
D O I：
10.1016/0165-1781(93)90112-T
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Although indirect evidence suggests that obstetric complications.are risk factors for bipolar disorder, few studies have directly addressed this question. Probands with bipolar disorder and their adult siblings were diagnosed according to DSM-III-R criteria by clinicians who had no knowledge of the subjects' obstetrical histories. Hospital records on gestations and births of 16 probands and 20 of their siblings without major mood disorders were scored for obstetric complications without knowledge of diagnosis. The assessment of obstetrical history was based on rating scales that have proved reliable and that reflect the number and severity of complications. Overall complication scores were significantly more severe in probands than siblings. Differences were most marked for perinatal complications.
引用
收藏
页码：47 / 56
页数：10
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