Targeted disruption of the IL-6 related genes: gp130 and NF-IL-6

被引：31
|
作者：
Akira, S [1 ]
Yoshida, K [1 ]
Tanaka, T [1 ]
Taga, T [1 ]
Kishimoto, T [1 ]
机构：
[1] OSAKA UNIV, SCH MED, DEPT MED 3, OSAKA, JAPAN
来源：
IMMUNOLOGICAL REVIEWS | 1995年 / 148卷
关键词：
D O I：
10.1111/j.1600-065X.1995.tb00100.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
[No abstract available]
引用
收藏
页码：221 / 253
页数：33
相关论文
共 50 条
  • [21] LEUKEMIA INHIBITORY FACTOR RECEPTOR IS STRUCTURALLY RELATED TO THE IL-6 SIGNAL TRANSDUCER, GP130
    GEARING, DP
    THUT, CJ
    VANDENBOS, T
    GIMPEL, SD
    DELANEY, PB
    KING, J
    PRICE, V
    COSMAN, D
    BECKMANN, MP
    EMBO JOURNAL, 1991, 10 (10): : 2839 - 2848
  • [22] Shedding of the interleukin-6 (IL-6) receptor (gp80) determines the ability of IL-6 to induce gp130 phosphorylation in human osteoblasts
    Vermes, C
    Jacobs, JJ
    Zhang, J
    Firneisz, G
    Roebuck, KA
    Glant, TT
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (19) : 16879 - 16887
  • [23] Hexameric structure and assembly of the interleukin-6/IL-6 α-receptor/gp130 complex
    Boulanger, MJ
    Chow, DC
    Brevnova, EE
    Garcia, KC
    SCIENCE, 2003, 300 (5628) : 2101 - 2104
  • [24] gp130 and the IL-6 family of cytokines: Signaling mechanisms and thrombopoietic activities
    Nakashima, K
    Taga, T
    SEMINARS IN HEMATOLOGY, 1998, 35 (03) : 210 - 221
  • [25] MOLECULAR-CLONING AND EXPRESSION OF AN IL-6 SIGNAL TRANSDUCER, GP130
    HIBI, M
    MURAKAMI, M
    SAITO, M
    HIRANO, T
    TAGA, T
    KISHIMOTO, T
    CELL, 1990, 63 (06) : 1149 - 1157
  • [26] Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis
    Hasegawa, M
    Sato, S
    Fujimoto, M
    Ihn, H
    Kikuchi, K
    Takehara, K
    JOURNAL OF RHEUMATOLOGY, 1998, 25 (02) : 308 - 313
  • [27] Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor to gp130 expression: fusing experimental insights and dynamic modelling
    Reeh, Heike
    Rudolph, Nadine
    Billing, Ulrike
    Christen, Henrike
    Streif, Stefan
    Bullinger, Eric
    Schliemann-Bullinger, Monica
    Findeisen, Rolf
    Schaper, Fred
    Huber, Heinrich J.
    Dittrich, Anna
    CELL COMMUNICATION AND SIGNALING, 2019, 17 (1)
  • [28] Molecular and functional characterization of IL-6 receptor (IL-6R) and glycoprotein 130 (gp130) in Nile tilapia (Oreochromis niloticus)
    Zhou, Enxu
    Yan, Fangfang
    Li, Bingxi
    Chen, Meng
    Tu, Xiao
    Wu, Siwei
    Wu, Hairong
    Wei, Xiufang
    Fu, Shengli
    Wu, Liting
    Guo, Zheng
    Ye, Jianmin
    DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2020, 106
  • [29] T cell hyperreactivity to IL-6 in chronic nonviremic HBV carriers despite normal IL-6 receptor or gp130 expression
    Baroja, ML
    Sirit, FL
    Rivera, H
    Garzaro, J
    Bianco, NE
    Machado, IV
    VIRAL IMMUNOLOGY, 1996, 9 (03) : 187 - 194
  • [30] Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling
    Heike Reeh
    Nadine Rudolph
    Ulrike Billing
    Henrike Christen
    Stefan Streif
    Eric Bullinger
    Monica Schliemann-Bullinger
    Rolf Findeisen
    Fred Schaper
    Heinrich J. Huber
    Anna Dittrich
    Cell Communication and Signaling, 17
12345