Cases of Wegener's granulomatosis with exclusive renal involvement are very unusual. Here we report a patient who presented which acute renal failure with massive extracapillary proliferation on renal biopsy, without extrarenal manifestations. After 9 years on chronic hemodialysis she developed several otorhinological abnormalities and finally pulmonary nodes. Lung biopsy showed a granulomatous vasculitis characteristic of Wegener's granulomatosis. Wegener's disease can recur after prolonged asymptomatic periods. In those cases with exclusive renal involvement, diagnosis can be delayed until the appearance of respiratory manifestations.
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Univ Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, ItalyUniv Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, Italy
Del Porto, F.
Proietta, M.
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Univ Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, ItalyUniv Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, Italy
Proietta, M.
Stoppacciaro, A.
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Univ Roma La Sapienza, Dipartimento Med Sperimentale, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, ItalyUniv Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, Italy
Stoppacciaro, A.
Trappolini, M.
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Univ Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, ItalyUniv Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, Italy
Trappolini, M.
Mene, P.
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Univ Roma La Sapienza, Dipartimento Sci Chim, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, ItalyUniv Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, Italy
Mene, P.
Aliberti, G.
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Univ Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, ItalyUniv Roma La Sapienza, Dipartimento Sci Med, Fac Med & Chirurg 2, Azienda Osped St Andrea, I-00189 Rome, Italy