OBSERVER DISAGREEMENT IN RATING NEUROLOGIC IMPAIRMENT IN MULTIPLE-SCLEROSIS - FACTS AND CONSEQUENCES

被引：29
|
作者：
VERDIERTAILLEFER, MH
ZUBER, M
LYONCAEN, O
CLANET, M
GOUT, O
LOUIS, C
ALPEROVITCH, A
机构：
[1] HOP LA PITIE SALPETRIERE,PARIS,FRANCE
[2] HOP PURPAN,TOULOUSE,FRANCE
来源：
EUROPEAN NEUROLOGY | 1991年 / 31卷 / 02期
关键词：
MULTIPLE SCLEROSIS; DISABILITY SCALE; INTEROBSERVER VARIABILITY; CLINICAL TRIALS;
D O I：
10.1159/000116658
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The interobserver variability of the expanded disability status scale (EDSS) was studied in 59 patients with multiple sclerosis (MS). Interrater agreement was measured by the kappa coefficient. Agreement was low in patients with mild disability (EDSS < 5); it was higher in patients with EDSS equal to or greater than 5. The difference between ratings of 2 independent examiners was equal to at least 1 point in 34% of the MS cases. This variability must be taken into consideration in designing clinical trials in MS.
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页码：117 / 119
页数：3
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