RESISTANCE TO THE POLYETHER IONOPHORE ANTIBIOTIC PANDAVIR (NIGERICIN) IN 2 PRODUCING STRAINS OF STREPTOMYCES

被引：1

作者：

MONCHEVA, PA ^{[1
]}

CHRISTOVA, KR ^{[1
]}

IVANOVA, IV ^{[1
]}

机构：

[1] UNIV SOFIA,DEPT MICROBIOL,BU-1000 SOFIA,BULGARIA

来源：

JOURNAL OF ANTIBIOTICS | 1995年 / 48卷 / 08期

关键词：

D O I：

10.7164/antibiotics.48.811

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In two pandavir (nigericin) producing strains, Streptomyces hygroscopicus 155 and Streptomyces albogriseolus 444, an enzyme activity was detected leading to inactivation of the antibiotic in the presence of ATP-Na-2. Apparently, the observed inactivation is specific for the antibiotic produced by these strains. The nigericin producing strains were also found to be less permeable to pandavir than their non-producing variants.

引用

页码：811 / 814

页数：4

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