ACETOL - A USEFUL NEW PROTECTING GROUP FOR PEPTIDE-SYNTHESIS

被引：9

作者：

KUNDU, B

机构：

[1] Division of Biopolymers Central Drug Research Institute, Lucknow

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(00)79849-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acetol can be conveniently used as a reagent for the protection of carboxylic acids in peptide synthesis. It has been found to be inert and stable to hydrogenolytic and acidolytic conditions normally used in peptide synthesis. Deblocking has been selectively achieved under mild conditions using Bu4NF.3H2O in THF.

引用

页码：3193 / 3196

页数：4

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