MOLECULAR-BIOLOGY OF THE RENIN-ANGIOTENSIN SYSTEM - IMPLICATIONS FOR HYPERTENSION AND BEYOND

被引：0
|
作者：
SAMANI, NJ [1 ]
机构：
[1] UNIV LEICESTER,DEPT MED,LEICESTER LE1 7RH,ENGLAND
来源：
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY | 1991年 / 18卷
基金：
英国惠康基金;
关键词：
RENIN-ANGIOTENSIN SYSTEM; MOLECULAR BIOLOGY; HYPERTENSION; TISSUE RENIN-ANGIOTENSIN SYSTEMS; RENIN INHIBITORS;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In the last decade, nucleic acid sequences coding for all three components of the renin-angiotensin cascade have been cloned. This has led to increased understanding of the transcriptional and translational regulation of renin, angiotensinogen, and angiotensin-converting enzyme (ACE). This review discusses the impact of the availability of these clones in three clinically relevant areas-the role of the renin-angiotensin system in hypertension, the role of tissue renin-angiotensin systems, and the development of renin inhibitors.
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页码：S1 / S6
页数：6
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