MOLECULAR-BIOLOGY OF THE RENIN-ANGIOTENSIN SYSTEM - IMPLICATIONS FOR HYPERTENSION AND BEYOND

被引：0

作者：

SAMANI, NJ ^{[1
]}

机构：

[1] UNIV LEICESTER,DEPT MED,LEICESTER LE1 7RH,ENGLAND

来源：

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY | 1991年 / 18卷

基金：

英国惠康基金;

关键词：

RENIN-ANGIOTENSIN SYSTEM; MOLECULAR BIOLOGY; HYPERTENSION; TISSUE RENIN-ANGIOTENSIN SYSTEMS; RENIN INHIBITORS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In the last decade, nucleic acid sequences coding for all three components of the renin-angiotensin cascade have been cloned. This has led to increased understanding of the transcriptional and translational regulation of renin, angiotensinogen, and angiotensin-converting enzyme (ACE). This review discusses the impact of the availability of these clones in three clinically relevant areas-the role of the renin-angiotensin system in hypertension, the role of tissue renin-angiotensin systems, and the development of renin inhibitors.

引用

页码：S1 / S6

页数：6

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