Five cases of tonsillectomy and steroid pulse therapy for recurrent immunoglobulin A nephropathy after kidney transplantation

被引：0
|
作者：
Hoshino, Yoshie [1 ]
Abe, Yasutomo [2 ]
Endo, Mariko [2 ]
Wakai, Sachiko [2 ]
Shirakawa, Hiroki [3 ]
Hotta, Osamu [4 ]
Ishida, Hideki [5 ]
Tanabe, Kazunari [5 ]
Tsuchiya, Ken [1 ]
Nitta, Kosaku [1 ]
机构：
[1] Tokyo Womens Med Univ, Kidney Ctr, Dept Med, Shinjuku Ku, 8-1 Kawada Cho, Tokyo 1628666, Japan
[2] Tokyo Metropolitan Hlth & Med Treatment Corp, Okubo Hosp, Dept Nephrol, Tokyo, Japan
[3] Tokyo Metropolitan Hlth & Med Treatment Corp, Okubo Hosp, Dept Transplantat, Tokyo, Japan
[4] Hotta Osamu Clin, Miyagi, Japan
[5] Tokyo Womens Med Univ, Dept Urol, Tokyo, Japan
来源：
CEN CASE REPORTS | 2014年 / 3卷 / 01期
关键词：
Recurrent IgA nephropathy; Tonsillectomy; Steroid pulse; Kidney transplantation;
D O I：
10.1007/s13730-013-0098-6
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Five cases of recurrent immunoglobulin A nephropathy (IgAN) after kidney transplantation were successfully treated by tonsillectomy and steroid pulse therapy (SPT). The clinical background and pathology in the five cases were different, but good results were obtained in all of them. In cases 1 and 2, mild recurrent IgAN developed and failed to remit after tonsillectomy alone, but a remission was achieved in both cases after SPT. In case 3, highly active recurrent IgAN with crescent lesions developed 13 years after kidney transplantation, and a remission was achieved after SPT. In case 4, renal biopsy specimens showed pathological findings of recurrent IgAN with tubulitis, and hematuria and proteinuria resolved after SPT. In case 5, the biopsy findings indicated recurrent IgAN with chronic rejection. Tonsillectomy was followed by resolution of the proteinuria, and a remission was achieved after SPT. In conclusion, SPT is effective in inducing a remission of recurrent IgAN when tonsillectomy alone fails.
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收藏
页码：118 / 122
页数：5
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