DIARYL ETHER/CARBOXYLIC ACID-DERIVATIVES OF LY255283 - RECEPTOR ANTAGONISTS OF LEUKOTRIENE B-4

被引：0
|
作者：
SAWYER, JS [1 ]
BALDWIN, RF [1 ]
SAUSSY, DL [1 ]
FROELICH, LL [1 ]
JACKSON, WT [1 ]
机构：
[1] PFIZER INC,CENT RES,GROTON,CT 06340
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 10期
关键词：
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The preparation and activity of a series of hydroxyacetophenone/diaryl ether LTB(4) receptor antagonists are described. The key acid-substituted diaryl ether moiety is discussed in relation to the spatial and functional group requirements of the LTB(4) receptor.
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页码：1985 / 1990
页数：6
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