NEW HYPOXANTHINE NUCLEOSIDES WITH RNA ANTIVIRAL ACTIVITY

被引：23
|
作者：
NAIR, V [1 ]
USSERY, MA [1 ]
机构：
[1] USA,MED RES INST INFECT DIS,DIV VIROL,FREDERICK,MD 21701
来源：
ANTIVIRAL RESEARCH | 1992年 / 19卷 / 02期
关键词：
EXOTIC RNA VIRUS; HYPOXANTHINE NUCLEOSIDE; ANTIVIRAL ACTIVITY;
D O I：
10.1016/0166-3542(92)90076-H
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A series of novel C-2 functionalized hypoxanthine and purine ribonucleosides have been synthesized and evaluated against exotic RNA viruses of the family or genus alpha, arena, flavi, and rhabdo. Both specific and broad-spectrum antiviral activities were discovered but only with hypoxanthine nucleosides.
引用
收藏
页码：173 / 178
页数：6
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