Cell-based models of blood-brain barrier penetration

被引：4
|
作者：
Vastag, Monika [1 ]
Hellinger, Eva [1 ]
Bakk, Monika L. [1 ]
Tihanyi, Karoly [1 ]
机构：
[1] Gedeon Richter Plc, Div Pharmacol & Drug Safety Res, Gyomroi Ut 19-21, H-1103 Budapest, Hungary
来源：
THERAPEUTIC DELIVERY | 2011年 / 2卷 / 05期
关键词：
blood-brain barrier; brain: plasma ratio; cell-based blood-brain barrier model; CNS penetration; efflux; surrogate blood-brain barrier model;
D O I：
10.4155/TDE.11.35
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The emerging new principle involves making a clear distinction between the permeation rate and the extent of brain distribution in a steady-state condition. . .
引用
收藏
页码：549 / 553
页数：5
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