CHANGES IN SEMANTIC MEMORY IN EARLY-STAGE ALZHEIMERS-DISEASE PATIENTS

被引：28
|
作者：
WEINGARTNER, HJ [1 ]
KAWAS, C [1 ]
RAWLINGS, R [1 ]
SHAPIRO, M [1 ]
机构：
[1] JOHNS HOPKINS UNIV,DEPT NEUROL,BALTIMORE,MD 21218
来源：
GERONTOLOGIST | 1993年 / 33卷 / 05期
关键词：
SEMANTIC MEMORY; AGING; ALZHEIMERS DISEASE; IMPAIRMENT; KNOWLEDGE; DEMENTIA; MODELS; FAILURE;
D O I：
10.1093/geront/33.5.637
中图分类号：
R4 [临床医学]; R592 [老年病学];
学科分类号：
1002 ; 100203 ; 100602 ;
摘要：
The types and number of exemplars of categories that are retrieved from semantic memory differentiate elderly normal controls and early stage Alzheimer's disease (AD) patients. Elderly normal controls generated more uncommon exemplars from closed semantic categories (fruits and vegetables) than did AD patients 2 1/2 years prior to the presumed onset of AD. AD patients, however, were just as productive as elderly normal controls in generating associations to open categories (letters). The findings suggest that one of the early cognitive symptoms of AD is changes in availability of uncommon exemplars of semantic networks.
引用
收藏
页码：637 / 643
页数：7
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