Immune reconstitution disorders in HIV patients receiving antiretroviral therapy

被引:0
|
作者
French, Martyn A. [1 ,2 ,3 ,4 ]
机构
[1] Univ Western Australia, Sch Pathol, Perth, WA, Australia
[2] Univ Western Australia, Lab Med, Perth, WA, Australia
[3] Royal Perth Hosp, Dept Clin Immunol, Perth, WA, Australia
[4] PathWest Lab Med, Perth, WA, Australia
关键词
D O I
10.1071/MA14030
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Suppression of HIV infection by antiretroviral therapy (ART) resolves much of the immune dysfunction caused by HIV replication. However, reconstitution of the immune system during ART may, paradoxically, cause immunological disease that presents clinically as an immune reconstitution disorder. These disorders include autoimmune disease, mainly Graves' disease, and immune-mediated inflammatory disease, such as sarcoidosis. However, by far the most common type of immune reconstitution disorder results from restoring immune responses against opportunistic pathogens.
引用
收藏
页码:97 / 98
页数:2
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