Pathobiology of ALK-negative anaplastic large cell lymphoma

被引：9
|
作者：
Pileri, Stefano A. [1 ]
Agostinelli, Claudio [1 ]
Bacci, Francesco [1 ]
Sabattini, Elena [1 ]
Sagramoso, Carlo [1 ]
Falini, Brunangelo [2 ]
Piccaluga, Pier Paolo [1 ]
机构：
[1] Univ Bologna, L&A Seragnoli S Orsola Malpighi Hosp, Dept Hematol & Oncol Sci, Hematopathol Sect, Bologna, Italy
[2] Univ Perugia, Silvestrini Hosp, Inst Hematol, Perugia, Italy
来源：
PEDIATRIC REPORTS | 2011年 / 3卷
关键词：
ALK-negative anaplastic large cell lymphoma;
D O I：
10.4081/pr.2011.s2.e5
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The authors revise the concept of ALK-negative anaplastic large cell lymphoma (ALCL) in the light of the recently updated WHO classification of Tumors of Hematopoietic and Lymphoid Tissues both on biological and clinical grounds. The main histological findings are illustrated as well as the phenotypic, molecular and clinical characteristics. Finally, the biological rationale for possible innovative targeted therapies is presented.
引用
收藏
页码：8 / 10
页数：3
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