N-3-HETEROARYLSUBSTITUTED-1-METHYL-2-PROPYNYL-N-HYDROXYUREAS, POTENT ORALLY-ACTIVE 2ND-GENERATION 5-LIPOXYGENASE INHIBITORS WITH ENHANCED DURATION OF ACTION

被引：0

作者：

BROOKS, DW ^{[1
]}

STEWART, AO ^{[1
]}

BASHA, A ^{[1
]}

BHATIA, P ^{[1
]}

RATAJCZYK, JD ^{[1
]}

CRAIG, R ^{[1
]}

BELL, RL ^{[1
]}

BOUSKA, JB ^{[1
]}

CARTER, GW ^{[1
]}

机构：

[1] ABBOTT LABS,IMMUNOSCI RES AREA,N CHICAGO,IL 60064

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1993年 / 206卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：41 / MEDI

共 50 条

[1] N-SUBSTITUTED DIHYDROISOQUINOLINONES - A SERIES OF POTENT, ORALLY-ACTIVE 5-LIPOXYGENASE INHIBITORS WITH AN EXTENDED DURATION OF ACTION IN-VIVO
VANDUZER, JH
ROLAND, DM
FRAIN, L
PINKERTON, M
PEREZ, J
MACCHIA, W
KIMBLE, EF
KOWALSKI, TJ
BLANCUZZI, V
PETERS, PA
CHERTOCK, H
KOTYUK, B
RAYCHAUDHURI, A
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 207 : 118 - MEDI
[2] DERIVATIVES OF 2-[[N-(AMINOCARBONYL)-N-HYDROXYAMINO]METHYL]-1,4-BENZODIOXAN AS ORALLY-ACTIVE 5-LIPOXYGENASE INHIBITORS
SATOH, Y
POWERS, C
TOLEDO, LM
KOWALSKI, TJ
PETERS, PA
KIMBLE, EF
JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (01) : 68 - 75
[3] AMIDE-LINKED N-HYDROXYUREAS - A NEW CLASS OF POTENT, LONG-LIVED AND ORALLY ACTIVE 5-LIPOXYGENASE INHIBITORS
DELLARIA, JF
SALLIN, KJ
MOORE, JL
BELL, RL
LANNI, C
BOUSKA, J
YOUNG, PR
BROOKS, DW
CARTER, GW
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1992, 204 : 104 - MEDI
[4] (R)-(+)-N-[3-[5-[(4-FLUOROPHENYL)METHYL]-2-THIENYL]-1-METHYL-2-PROPYNYL]-N-HYDROXYUREA (ABT-761), A 2ND-GENERATION 5-LIPOXYGENASE INHIBITOR
BROOKS, CDW
STEWART, AO
BASHA, A
BHATIA, P
RATAJCZYK, JD
MARTIN, JG
CRAIG, RA
KOLASA, T
BOUSKA, JB
LANNI, C
HARRIS, RR
MALO, PE
CARTER, GW
BELL, RL
JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (24) : 4768 - 4775
[5] SUBSTITUTED THIOPYRANO[2,3,4-C,D]INDOLES AS POTENT, SELECTIVE AND ORALLY-ACTIVE INHIBITORS OF 5-LIPOXYGENASE - DEVELOPMENT AND BIOLOGICAL PROFILE OF L-699,333
THERIEN, M
BRIDEAU, C
CHAN, C
FALGUEYRET, JP
GUAY, J
JONES, TR
LEPINE, C
MACDONALD, D
MCFARLANE, CS
PIECHUTA, H
RIENDEAU, D
SCHEIGETZ, J
TAGARI, P
HUTCHINSON, JH
GIRARD, Y
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 206 : 39 - MEDI
[6] SUBSTITUTED THIOPYRANO[2,3,4-C,D]INDOLES AS POTENT, SELECTIVE, AND ORALLY-ACTIVE INHIBITORS OF 5-LIPOXYGENASE - SYNTHESIS AND BIOLOGICAL EVALUATION OF L-691,816
HUTCHINSON, JH
RIENDEAU, D
BRIDEAU, C
CHAN, C
DELORME, D
DENIS, D
FALGUEYRET, JP
FORTIN, R
GUAY, J
HAMEL, P
JONES, TR
MACDONALD, D
MCFARLANE, CS
PIECHUTA, H
SCHEIGETZ, J
TAGARI, P
THERIEN, M
GIRARD, Y
JOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (19) : 2771 - 2787
[7] SUBSTITUTED THIOPYRANO[2,3,4-C,D]INDOLES AS POTENT, SELECTIVE AND ORALLY ACTIVE INHIBITORS OF 5-LIPOXYGENASE - SYNTHESIS AND SAR STUDIES
MACDONALD, D
HUTCHINSON, JH
DENIS, D
FALGUEYRET, JP
GUAY, J
RIENDEAU, D
SCHEIGETZ, J
THERIEN, M
GIRARD, Y
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 205 : 139 - MEDI
[8] 1-PHENYL-[2H]-TETRAHYDROPYRIDAZIN-3-ONE, A SERIES OF SELECTIVE, ORALLY ACTIVE 5-LIPOXYGENASE INHIBITORS
BROOKS, DW
KERDESKY, FAJ
HOLMS, JH
SCHMIDT, SP
BASHA, A
RATAJCZYK, JD
MARTIN, JG
YOUNG, PR
ALBERT, DH
DYER, RD
BOUSKA, JB
CARTER, GW
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1988, 196 : 121 - MEDI
[9] SUBSTITUTED THIOPYRANO[2,3,4-C,D]INDOLES AS POTENT, SELECTIVE AND ORALLY ACTIVE INHIBITORS OF 5-LIPOXYGENASE - DEVELOPMENT OF L-691,816
HUTCHINSON, JH
CHAN, C
DELORME, D
DENIS, D
FALGUEYRET, JP
FORTIN, R
GUAY, J
HAMEL, P
JONES, TR
MACDONALD, D
MCFARLANE, CS
PIECHUTA, H
RIENDEAU, D
SCHEIGETZ, J
TAGARI, P
THERIEN, M
GIRARD, Y
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 205 : 140 - MEDI
[10] 4-METHYL-5-AMINO-1-FORMYLISOQUINOLINE THIOSEMICARBAZONE, A 2ND-GENERATION ANTINEOPLASTIC AGENT OF ALPHA-(N)-HETEROCYCLIC CARBOXALDEHYDE THIOSEMICARBAZONE SERIES
AGRAWAL, KC
SCHENKMAN, JB
DENK, H
MOONEY, PD
MOORE, EC
WODINSKY, I
SARTORELLI, AC
CANCER RESEARCH, 1977, 37 (06) : 1692 - 1696

← 1 2 3 4 5 →