COMPOUNDS RELATED TO ACYCLOVIR .9. SYNTHESIS OF 4-HYDROXY-2,5-DIOXAHEPTYL DERIVATIVES OF NUCLEIC BASES

被引：0

作者：

SMIRNOV, IP ^{[1
]}

TSILEVICH, TL ^{[1
]}

KOCHETKOVA, SV ^{[1
]}

GOTTIKH, BP ^{[1
]}

SHCHAVELEVA, IL ^{[1
]}

FLORENTEV, VL ^{[1
]}

机构：

[1] RUSSIAN ACAD SCI, VA ENGELHARDT MOLEC BIOL INST, MOSCOW 117984, RUSSIA

来源：

BIOORGANICHESKAYA KHIMIYA | 1995年 / 21卷 / 10期

关键词：

NUCLEIC BASES; ACYCLIC NUCLEOSIDES; SYNTHESIS; ACYCLOVIR; RIBAVIRIN; ANALOGS;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

7-Hydroxy-2,5-dioxaheptyl and racemic 7-hydroxy-1-methyl-2,5-dioxaheptyl derivatives of uracil, thymine, cytosine, adenine, guanine, and 1,2,4-triazole-3-carboxamide were synthesized using 7-acetyloxy-1-chlor-2,5-dioxaheptane and 8-acetyloxy-2-chlor-3,6-dioxaoctane as alkylating agents.

引用

页码：790 / 794

页数：5

共 49 条

[31] Synthesis of N9- and N7-[2-hydroxy-3-(phosphonomethoxy)propyl] derivatives of N6-substituted adenines, 2,6-diaminopurines and related compounds
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[32] Synthesis and biological evaluation of 9-[2-fluoro-4-hydroxy-3-hydroxymethyl-2-butenyl]adenine and its related compounds as open-chain analogues of neplanocin A
Choi, MH
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[33] Synthesis and biological evaluation of 9-[2-fluoro-4-hydroxy-3-hydroxymethyl-2-butenyl]adenine and its related compounds as open-chain analogues of neplanocin A
Myung-Hee Choi
Hee-Doo Kim
Archives of Pharmacal Research, 1997, 20 : 501 - 506
[34] DEAZAPURINE DERIVATIVES .9. SYNTHESIS OF (7-SUBSTITUTED)-1-, 2- AND 3-BETA-D-RIBOFURANOSYL-VIC-TRIAZOLO[4,5-B]PYRIDINES - 1-DEAZA-8-AZA-ADENOSINE AND RELATED COMPOUNDS
ROOS, KBD
SALEMINK, CA
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[35] TIN(IV) CHLORIDE-PROMOTED REACTIONS OF ALPHA-HYDROXY NITRILES WITH BETA-DICARBONYL COMPOUNDS - SYNTHESIS OF 4-AMINO-2,5-DIHYDRO-2-FURANONES AND THEIR CONVERSION INTO TETRONIC ACID-DERIVATIVES
VERONESE, AC
CALLEGARI, R
BERTAZZO, A
HETEROCYCLES, 1991, 32 (11) : 2205 - 2215
[36] STUDIES ON INDENOPYRIDINE DERIVATIVES AND RELATED COMPOUNDS .2. STEREOCHEMISTRY OF 1-SUBSTITUTED 9-PHENYL-1,3,4,4A,9,9A-HEXAHYDRO-4-HYDROXY-2H-INDENO[2,1-B]PYRIDINES AND THEIR ACETATES
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JOURNAL OF HETEROCYCLIC CHEMISTRY, 1975, 12 (02) : 221 - 224
[37] RESEARCH ON SUBSTANCES WITH ANTIBLASTIC ACTIVITY .60. ANTHRAMYCIN AND SOME ANALOGS .9. SYNTHESIS OF 7-METHOXY-8-HYDROXY-10,11-DIHYDRO-5H-PYRROLO(2,1-C) (1,4) BENZODIAZEPIN AND OTHER COMPOUNDS RELATED WITH OXOTOMAYMYCIN
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FARMACO-EDIZIONE SCIENTIFICA, 1977, 32 (08): : 579 - 591
[38] STUDIES ON INDENOPYRIDINE DERIVATIVES AND RELATED-COMPOUNDS .4. SYNTHESIS AND STEREOCHEMISTRY OF ETHYL 9,9-DIMETHYL-1,2,3,9A-TETRAHYDRO-9H-INDENO[2,1-B]PYRIDINE-3-CARBOXYLATE AND ITS DERIVATIVES
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[39] NUCLEIC-ACID RELATED-COMPOUNDS .50. SYNTHESIS AND CONFORMATIONAL STUDIES OF 4-CARBAMOYL-1-[(2-HYDROXYETHOXY)-METHYL]-5-(METHYLAMINO)IMIDAZOLE AND DERIVATIVES AS NEW ACYCLONUCLEOSIDE ANALOGS
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HATFIELD, PW
ROBINS, MJ
HETEROCYCLES, 1987, 25 : 493 - 506
[40] PYRIMIDINE-DERIVATIVES AND RELATED COMPOUNDS .9. PREPARATION OF 5-AMINOPYRAZOLO[1,5-A]PYRIMIDINES AND OF OXAZINO[4,5-5,6]PYRAZOLO[1,5-A]PYRIMIDINES, A NEW RING-SYSTEM
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