COMPOUNDS RELATED TO ACYCLOVIR .9. SYNTHESIS OF 4-HYDROXY-2,5-DIOXAHEPTYL DERIVATIVES OF NUCLEIC BASES

被引：0
|
作者：
SMIRNOV, IP [1 ]
TSILEVICH, TL [1 ]
KOCHETKOVA, SV [1 ]
GOTTIKH, BP [1 ]
SHCHAVELEVA, IL [1 ]
FLORENTEV, VL [1 ]
机构：
[1] RUSSIAN ACAD SCI, VA ENGELHARDT MOLEC BIOL INST, MOSCOW 117984, RUSSIA
来源：
BIOORGANICHESKAYA KHIMIYA | 1995年 / 21卷 / 10期
关键词：
NUCLEIC BASES; ACYCLIC NUCLEOSIDES; SYNTHESIS; ACYCLOVIR; RIBAVIRIN; ANALOGS;
D O I：
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学科分类号：
摘要：
7-Hydroxy-2,5-dioxaheptyl and racemic 7-hydroxy-1-methyl-2,5-dioxaheptyl derivatives of uracil, thymine, cytosine, adenine, guanine, and 1,2,4-triazole-3-carboxamide were synthesized using 7-acetyloxy-1-chlor-2,5-dioxaheptane and 8-acetyloxy-2-chlor-3,6-dioxaoctane as alkylating agents.
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页码：790 / 794
页数：5
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