Non-vitamin K antagonist oral anticoagulants (NOAC) in chronic kidney disease. Recommendations of the working group "Heart-Kidneys", of the German Cardiac Society and the German Society of Nephrology

被引：0

作者：

Schlieper, G. ^{[1
,2
]}

Remppis, A. ^{[3
]}

Schwenger, V. ^{[4
]}

Keller, T. ^{[5
]}

Dechend, R. ^{[6
,7
]}

Massberg, S. ^{[8
]}

Baldus, S. ^{[9
]}

Weinreich, T. ^{[10
]}

Hetzel, G. ^{[11
]}

Floege, J. ^{[2
]}

Hoyer, J. ^{[12
]}

Mahfoud, F. ^{[13
,14
]}

Fliser, D. ^{[15
]}

机构：

[1] Zentrum Nieren Hochdruck & Stoffwechselerkrankung, Heidering 31, D-30625 Hannover, Germany

[2] Uniklin RWTH Aachen, Klin Nieren & Hochdruckkrankheiten, Rheumatol & Immunol Erkrankungen, Med Klin 2, Aachen, Germany

[3] Herz & Gefasszentrum, Klin Kardiol, Bad Bevensen, Germany

[4] Klinikum Stuttgart, Klin Nieren & Hochdruckkrankheiten, Transplantat Zentrum, Stuttgart, Germany

[5] Univ Klinikum Frankfurt, Med Klin Kardiol 3, Angiol, Nephrol, Frankfurt, Germany

[6] Klinikum Berlin, HELIOS, Berlin, Germany

[7] Charite Campus Buch, Expt & Clin Res Ctr, Berlin, Germany

[8] Klinikum Univ Munchen, Med Klin & Poliklin 1, Munich, Germany

[9] Univ Cologne, Herzzentrum, Klin Kardiol Angiol Pneumol & Internist Intens Me, Cologne, Germany

[10] Nephrol Zentrum Villingen Schwenningen, Villingen Schwenningen, Germany

[11] MVZ DaVita Rhein Ruhr, Dusseldorf, Germany

[12] Klinikum Philipps Univ, Innere Med Klin, Nephrol & Internist Intens Med, Marburg, Germany

[13] MIT, Inst Med Engn & Sci, Cambridge, MA 02139 USA

[14] Univ Klinikum Saarlandes, Klin Innere Med Kardiol Angiol & Internist Intens, Homburg, Germany

[15] Univ Klinikum Saarlandes, Klink Innere Med Nieren & Hochdruckkrankheiten 4, Homburg, Germany

来源：

NEPHROLOGE | 2018年 / 13卷 / 02期

关键词：

Anticoagulation; Dabigatran; Rivaroxaban; Apixaban; Edoxaban;

D O I：

10.1007/s11560-018-0230-x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Non-vitamin K antagonist oral anticoagulants (NOAC) are administered for stroke prophylaxis in patients with atrial fibrillation and corresponding risk scores. In addition, NOAC are used for treatment and prophylaxis of venous thromboembolic events, such as deep vein thrombosis and acute pulmonary embolism and their prophylaxis in recurrent events. Clinical trials have excluded patients with advanced chronic kidney disease; therefore, data cannot always be generalized to patients with chronic kidney disease. The use of NOAC is not recommended or is contraindicated in advanced stages of chronic kidney disease.

引用

页码：91 / 98

页数：8

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