It is obviously impossible to determine whether corpus callosotomy is an under-or overutilized procedure in children. However, consistent results for the procedure performed on carefully selected patients have been reported from major epilepsy centers. The procedure generally is well tolerated in children, with very few reported adverse effects. The procedure has been used in the most severe of epileptics with favorable results when patients are selected with the goal of ameliorating generalized atonic, myoclonic, tonic, and tonic-clonic seizures. Well-designed prospective studies are certainly needed to better understand the outcomes of callosotomy, but, until these studies are available, children with severe intractable epilepsy should at least have the procedure considered in the management of their condition.
机构:
Univ Western Ontario, Univ Hosp, Epilepsy Unit, London, ON N6A 5A5, CanadaUniv Western Ontario, Univ Hosp, Epilepsy Unit, London, ON N6A 5A5, Canada
Blume, WT
PAEDIATRIC EPILEPSY SYNDROMES AND THEIR SURGICAL TREATMENT,
1997,
11
: 815
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829
机构:
Osaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, Japan
Osaka City Gen Hosp, Dept Pediat Neurosurg, Osaka 5340021, JapanOsaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, Japan
Uda, Takehiro
Kunihiro, Noritsugu
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Osaka City Gen Hosp, Dept Pediat Neurosurg, Osaka 5340021, JapanOsaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, Japan
Kunihiro, Noritsugu
Umaba, Ryoko
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Osaka City Gen Hosp, Dept Pediat Neurosurg, Osaka 5340021, JapanOsaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, Japan
Umaba, Ryoko
Koh, Saya
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Osaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, JapanOsaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, Japan
Koh, Saya
Kawashima, Toshiyuki
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Osaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, JapanOsaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, Japan
Kawashima, Toshiyuki
Ikeda, Shohei
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Osaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, JapanOsaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, Japan
Ikeda, Shohei
Ishimoto, Kotaro
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Osaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, JapanOsaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, Japan
Ishimoto, Kotaro
Goto, Takeo
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Osaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, JapanOsaka City Univ, Grad Sch Med, Dept Neurosurg, Osaka 5458585, Japan