IMAGE-PROCESSING FOR ONLINE MONITORING OF GRANULE SIZE DISTRIBUTION AND SHAPE IN FLUIDIZED-BED GRANULATION

被引：86
|
作者：
WATANO, S
MIYANAMI, K
机构：
[1] Department of Chemical Engineering, University of Osaka Prefecture, Sakai, Osaka, 593
来源：
POWDER TECHNOLOGY | 1995年 / 83卷 / 01期
关键词：
GRANULATION; ONLINE MONITORING; PARTICLE IMAGE PROBE; IMAGE PROCESSING SYSTEM; GRANULE GROWTH; FLUIDIZED BED;
D O I：
10.1016/0032-5910(94)02944-J
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
A particle image probe comprising a CCD camera and an image processing system has been developed for on-line monitoring of granule size distribution and shape in a fluidized bed granulation. Continuous granule measurements by the image probe were digitized and processed by the image processing system, and granule size distribution and shape were computed in real time. The developed system was applied to the monitoring of granule growth in pharmaceutical granulation and its validity was confirmed. Application of this system to the dynamic control of granule size and shape was also demonstrated.
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页码：55 / 60
页数：6
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