HYDROXYUREA ENHANCES FETAL HEMOGLOBIN PRODUCTION IN SICKLE-CELL-ANEMIA

被引:418
|
作者
PLATT, OS
ORKIN, SH
DOVER, G
BEARDSLEY, GP
MILLER, B
NATHAN, DG
机构
[1] HARVARD UNIV, SCH MED, DEPT PEDIAT, BOSTON, MA 02115 USA
[2] JOHNS HOPKINS UNIV HOSP, DEPT PEDIAT, BALTIMORE, MD 21205 USA
[3] DANA FARBER CANC INST, DIV PEDIATR, BALTIMORE, MD 21205 USA
来源
JOURNAL OF CLINICAL INVESTIGATION | 1984年 / 74卷 / 02期
关键词
D O I
10.1172/JCI111464
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:652 / 656
页数:5
相关论文
共 50 条
  • [31] HYDROXYUREA - AN ALTERNATIVE TO TRANSFUSION THERAPY FOR STROKE IN SICKLE-CELL-ANEMIA
    WARE, RE
    STEINBERG, MH
    KINNEY, TR
    [J]. AMERICAN JOURNAL OF HEMATOLOGY, 1995, 50 (02) : 140 - 143
  • [32] EFFECT OF HYDROXYUREA ON THE FREQUENCY OF PAINFUL CRISES IN SICKLE-CELL-ANEMIA
    CHARACHE, S
    TERRIN, ML
    MOORE, RD
    DOVER, GJ
    BARTON, FB
    ECKERT, SV
    MCMAHON, RP
    BONDS, DR
    ORRINGER, E
    JONES, S
    STRAYHORN, D
    ROSSE, W
    PHILLIPS, G
    PEACE, D
    JOHNSONTELFAIR, A
    MILNER, P
    KUTLAR, A
    TRACY, A
    BALLAS, SK
    ALLEN, GE
    MOSHANG, J
    SCOTT, B
    STEINBERG, M
    ANDERSON, A
    SABAHI, V
    PEGELOW, C
    TEMPLE, D
    CASE, E
    HARRELL, R
    CHILDERIE, S
    EMBURY, S
    SCHMIDT, B
    DAVIES, D
    KOSHY, M
    TALISCHYZAHED, N
    DORN, L
    PENDARVIS, G
    MCGEE, M
    TELFER, M
    DAVIS, A
    CASTRO, O
    FINKE, H
    PERLIN, E
    SITEMAN, J
    GASCON, P
    DIPAOLO, P
    GARGIULO, S
    ECKMAN, J
    BAILEY, JH
    PLATT, A
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (20): : 1317 - 1322
  • [33] Fetal hemoglobin in sickle cell anemia
    Steinberg, Martin H.
    [J]. BLOOD, 2020, 136 (21) : 2392 - 2400
  • [34] Fetal hemoglobin in sickle cell anemia
    Akinsheye, Idowu
    Alsultan, Abdulrahman
    Solovieff, Nadia
    Duyen Ngo
    Baldwin, Clinton T.
    Sebastiani, Paola
    Chui, David H. K.
    Steinberg, Martin H.
    [J]. BLOOD, 2011, 118 (01) : 19 - 27
  • [35] Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy
    Ware, RE
    Eggleston, B
    Redding-Lallinger, R
    Wang, WC
    Smith-Whitley, K
    Daeschner, C
    Gee, B
    Styles, LA
    Helms, RW
    Kinney, TR
    Ohene-Frempong, K
    [J]. BLOOD, 2002, 99 (01) : 10 - 14
  • [36] LACK OF INFLUENCE OF FETAL HEMOGLOBIN LEVELS OR ERYTHROCYTE INDEXES ON THE SEVERITY OF SICKLE-CELL-ANEMIA
    POWARS, DR
    SCHROEDER, WA
    WEISS, JN
    CHAN, LS
    AZEN, SP
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1980, 65 (03): : 732 - 740
  • [37] SICKLE-CELL-ANEMIA, A CONSTITUTIONAL ABNORMALITY OF HEMOGLOBIN STRUCTURE
    SCHAISON, G
    [J]. REVUE DE STOMATOLOGIE ET DE CHIRURGIE MAXILLO-FACIALE, 1983, 84 (03): : 144 - 148
  • [38] SPECTRUM OF FETAL HEMOGLOBIN RESPONSE IN PATIENTS WITH SICKLE ANEMIA TREATED WITH HYDROXYUREA
    RODGERS, GP
    DOVER, GJ
    NOGUCHI, CT
    SCHECHTER, AN
    NIENHUIS, AW
    [J]. CLINICAL RESEARCH, 1988, 36 (03): : A568 - A568
  • [39] Rheological properties of sickle erythrocytes in patients with sickle-cell anemia: The effect of hydroxyurea, fetal hemoglobin, and α-thalassemia
    Ballas, Samir K.
    Connes, Philippe
    [J]. EUROPEAN JOURNAL OF HAEMATOLOGY, 2018, 101 (06) : 798 - 803
  • [40] HIGH FETAL HEMOGLOBIN PRODUCTION IN SICKLE-CELL-ANEMIA IN THE EASTERN PROVINCE OF SAUDI-ARABIA IS GENETICALLY-DETERMINED
    MILLER, BA
    SALAMEH, M
    AHMED, M
    WAINSCOAT, J
    ANTOGNETTI, G
    ORKIN, S
    WEATHERALL, D
    NATHAN, DG
    [J]. BLOOD, 1986, 67 (05) : 1404 - 1410