GENETICS OF PSORIASIS AND PSORIATIC ARTHRITIS

被引：7
|
作者：
Mathieu, A. [1 ]
Cauli, A. [1 ]
Vacca, A. [1 ]
Mameli, A. [1 ]
Passiu, G. [1 ]
Porru, G. [1 ]
Piga, M. [1 ]
Ibba, V. [1 ]
Mura, V. [1 ]
Sanna, S. [1 ]
机构：
[1] Univ Cagliari, Chair Rheumatol, Cagliari, Italy
来源：
REUMATISMO | 2007年 / 59卷
关键词：
Genetics; psosriasis; psoriatic arthritis;
D O I：
10.4081/reumatismo.2007.1s.25
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Psoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied extensively; they include HLA genes, genes within the HLA region and genes outside the HLA region; among them corneodesmosin and other genes of PSORS1 region, MICA and TNF-alpha polymorphisms. The main findings in the literature are discussed.
引用
收藏
页码：25 / 27
页数：3
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