Effect and mechanism of ubiquitin-like protein FAT10 on AngⅡinduced endothelial cell inflammation

被引:0
|
作者
卓雯
机构
[1] 2nd Affil Hosp
[2] Nanchang Univ
[3] Dept Cardiovasc Med
关键词
D O I
暂无
中图分类号
R54 [心脏、血管(循环系)疾病];
学科分类号
摘要
Objective To investigate the role and related mechanism of ubiquitin-like protein FAT10 in the angiotensinⅡ(AngⅡ)-induced endothelial cell inflammatory responses.Methods The Western blot was used to detect the protein expression of FAT10 in 16-week old WKY rat carotid artery,thoracic aorta artery,renal artery and vascular smooth muscle cells (VSMC),
引用
收藏
页码:39 / 40
页数:2
相关论文
共 50 条
  • [41] The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition
    Kalveram, Birte
    Schmidtke, Gunter
    Groettrup, Marcus
    JOURNAL OF CELL SCIENCE, 2008, 121 (24) : 4079 - 4088
  • [42] The interaction partners of the ubiquitin like protein FAT10 may account for rapid targeting of FAT10 and its conjugates to degradation through the proteasome
    Groettrup, M
    Hipp, MS
    Raasi, S
    Schmidtke, G
    FASEB JOURNAL, 2003, 17 (05): : A995 - A996
  • [43] Modification of the inflammatory mediator LRRFIP2 by the ubiquitin-like protein FAT10 inhibits its activity during cellular response to LPS
    Buchsbaum, Samuel
    Bercovich, Beatrice
    Ziv, Tamar
    Ciechanover, Aaron
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 428 (01) : 11 - 16
  • [44] Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy
    Roverato, Nicola D.
    Sailer, Carolin
    Catone, Nicola
    Aichem, Annette
    Stengel, Florian
    Groettrup, Marcus
    CELL REPORTS, 2021, 34 (11):
  • [45] The ubiquitin-like modifier FAT10 lowers type I interferons and enhances interferon-γ after viral infection
    Mah, M. M.
    Basler, M.
    Groettrup, M.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 125 - 126
  • [46] The ubiquitin-like modifier FAT10 inhibits retinal PDE6 activity and mediates its proteasomal degradation
    Boehm, Annika N.
    Bialas, Johanna
    Catone, Nicola
    Sacristan-Reviriego, Almudena
    van der Spuy, Jacqueline
    Groettrup, Marcus
    Aichem, Annette
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 295 (42) : 14402 - 14418
  • [47] The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10
    Schmidtke, Gunter
    Kalveram, Birte
    Weber, Elvira
    Bochtler, Petra
    Lukasiak, Sebastian
    Hipp, Mark Steffen
    Groettrup, Marcus
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (29) : 20045 - 20054
  • [48] The ubiquitin-like protein FAT10 in hepatocellular carcinoma cells limits the efficacy of anti-VEGF therapy by accelerating VEGF-independent angiogenesis
    Qiu, Yumin
    Che, Ben
    Zhang, Wenming
    Ge, Jin
    Du, Dongnian
    Li, Jiajuan
    Peng, Xiaogang
    Shao, Jianghua
    JOURNAL OF ADVANCED RESEARCH, 2024, 59 : 97 - 109
  • [49] Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism
    Cappadocia, Laurent
    Lima, Christopher D.
    CHEMICAL REVIEWS, 2018, 118 (03) : 889 - 918
  • [50] Trans mechanism for ubiquitin-like protein transfer in autophagy
    Taherbhoy, Asad M.
    Kaiser, Stephen E.
    Schulman, Brenda A.
    CELL CYCLE, 2012, 11 (04) : 635 - 636