Identification and characterization of brt1, a gene down-regulated during B-regulated development in Schizophyllum commune

被引：0
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作者：
Klaus B. Lengeler
E. Kothe
机构：
[1] Friedrich-Schiller-Universität,
[2] Biologisch-Pharmazeutische Fakultät,undefined
[3] Institut für Mikrobiologie,undefined
[4] Mikrobielle Phytopathologie,undefined
[5] Beutenbergstrasse 11,undefined
[6] D-07745 Jena,undefined
[7] Germany e-mail: ekothe@pmail.hki-jena.de Tel.: +49-3641-657631 Fax: +49-3641-657633,undefined
来源：
Current Genetics | 1999年 / 35卷
关键词：
Key wordsSchizophyllum commune; Basidiomycete; Mating type; Regulation;
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摘要：
To identify genes regulated by the B mating-type genes a differential RNA display was established for the homobasidiomycete Schizophyllum commune and a gene, brt1, was identified. The mRNA concerned is highly abundant in monokaryotic mycelia and is down-regulated in matings in which either the B genes alone or else both the A and B genes are different between the mates. This places the gene brt1 under the control of the pheromone response system of S. commune encoded by the B mating-type loci. Sequence analysis revealed similarity to a novel protein family, two members of which have been shown to inhibit translational re-initiation.
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页码：551 / 556
页数：5
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