Synthesis, antimicrobial activity, pharmacophore modeling and molecular docking studies of new pyrazole-dimedone hybrid architectures

被引:0
|
作者
Assem Barakat
Abdullah M. Al-Majid
Bander M. Al-Qahtany
M. Ali
Mohamed Teleb
Mohamed H. Al-Agamy
Sehrish Naz
Zaheer Ul-Haq
机构
[1] King Saud University,Department of Chemistry, Faculty of Science
[2] Alexandria University,Department of Chemistry, Faculty of Science
[3] Alexandria University,Department of Pharmaceutical Chemistry, Faculty of Pharmacy
[4] Al-Azhar University,Microbiology and Immunology Department, Faculty of Pharmacy
[5] King Saud University,Division of Microbiology, Pharmaceutics Department, College of Pharmacy
[6] University of Karachi,Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences
来源
关键词
Pyrazole; Dimedone; Antifungal activity; Antimicrobial activity; Structure activity relationship; Inhibition mechanism prediction;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Molecular modeling and docking studies of new antimicrobial antipyrine-thiazole hybrids
    Abu-Melha, Sraa
    ARABIAN JOURNAL OF CHEMISTRY, 2022, 15 (07)
  • [32] Synthesis, Characterization, Antimicrobial Activity and Molecular Docking Studies of New Benzimidazole, Benzoxazole, Imidazole and Tetrazole Derivatives
    Arulmurugan, Subramaniyan
    Kavitha, Helen P.
    ORIENTAL JOURNAL OF CHEMISTRY, 2020, 36 (04) : 672 - 679
  • [33] Pharmacophore modeling, molecular docking, QSAR, and in silico ADMET studies of gallic acid derivatives for immunomodulatory activity
    Yadav, Dharmendra Kumar
    Khan, Feroz
    Negi, Arvind Singh
    JOURNAL OF MOLECULAR MODELING, 2012, 18 (06) : 2513 - 2525
  • [34] Pharmacophore modeling, molecular docking, QSAR, and in silico ADMET studies of gallic acid derivatives for immunomodulatory activity
    Dharmendra Kumar Yadav
    Feroz Khan
    Arvind Singh Negi
    Journal of Molecular Modeling, 2012, 18 : 2513 - 2525
  • [35] Synthesis, Anticancer Activity and Molecular Docking Studies of Pyrazole Conjugated Pthalazine-2-carbonitriles
    Kalpana, K.
    Rani, V. Anitha
    Yedla, P.
    Mohammed, S. Hussain
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2023, 93 (08) : 2076 - 2082
  • [36] Synthesis, Anticancer Activity and Molecular Docking Studies of Pyrazole Conjugated Pthalazine-2-carbonitriles
    K. Kalpana
    V. Anitha Rani
    P. Yedla
    S. Hussain Mohammed
    Russian Journal of General Chemistry, 2023, 93 : 2076 - 2082
  • [37] New library of pyrazole-imidazo[1,2-α]pyridine molecular conjugates: Synthesis, antibacterial activity and molecular docking studies
    Ebenezer, Oluwakemi
    Awolade, Paul
    Koorbanally, Neil
    Singh, Parvesh
    CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 95 (01) : 162 - 173
  • [38] Design, Synthesis, Antimicrobial and Docking Studies of Benzothiazoles Bearing Pyrazole and Pyrimidine Moieties
    Tamam, Esraa
    Fadda, Ahmed A.
    El-Sawy, Eslam R.
    Abdel-Aziz, Mohamed S.
    Tawfik, Eman H.
    CHEMISTRYSELECT, 2023, 8 (32):
  • [39] A new approach for the synthesis of tri-substituted pyrazole propionic acids derivatives: Anti-inflammatory, antimicrobial and molecular docking studies
    Gudimani, Parashuram
    Hebbar, Nagashree U.
    Shastri, Samundeeswari L.
    Shastri, Lokesh A.
    Shettar, Arun K.
    Hoskeri, Joy H.
    Joshi, Shrinivas
    Sunagar, Vinay A.
    JOURNAL OF MOLECULAR STRUCTURE, 2023, 1285
  • [40] Synthesis, Molecular Docking and In Vitro Antimicrobial Studies of New Hexahydroindazole Derivatives of Curcumin
    Kumar, Dileep
    Harish, B. G.
    Gangwar, Mayank
    Kumar, Manish
    Kumar, Dharmendra
    RaginiTilak
    Nath, Gopal
    Kumar, Ashok
    Singh, Sushil Kumar
    LETTERS IN DRUG DESIGN & DISCOVERY, 2013, 10 (02) : 119 - 128