MEX3A determines in vivo hepatocellular carcinoma progression and induces resistance to sorafenib in a Hippo-dependent way

被引：0

作者：

Shiji Fang

Liyun Zheng

Xiaoxiao Chen

Xiaoju Guo

Yiming Ding

Ji Ma

Jiayi Ding

Weiqian Chen

Yang Yang

Minjiang Chen

Zhongwei Zhao

Jianfei Tu

Jiansong Ji

机构：

[1] The Fifth Affiliated Hospital of Wenzhou Medical University,Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Institute of Imaging Diagnosis and Minimally Invasive Intervention Research

[2] Lishui University,Clinical College of The Affiliated Central Hospital, School of Medicine

[3] Lishui Hospital of Zhejiang University,Department of Radiology, School of Medicine

[4] Shaoxing University School of Medicine,undefined

来源：

Hepatology International | 2023年 / 17卷

关键词：

MEX3A; WWC1; Hippo signaling pathway; Hepatocellular carcinoma progression; Sorafenib sensitivity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：1500 / 1518

页数：18

共 19 条

[11] LncRNA SNHG3 induces EMT and sorafenib resistance by modulating the miR-128/CD151 pathway in hepatocellular carcinoma
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JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 234 (03) : 2788 - 2794
[12] Sorafenib and Its Derivative SC-59 Induces Autophagy in Hepatocellular Carcinoma Through SHP-1 Dependent Inhibition of STAT3
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Tai, W. T.
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Chen, P. J.
Chen, K. F.
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[13] CSF3R-AS promotes hepatocellular carcinoma progression and sorafenib resistance through the CSF3R/JAK2/STAT3 positive feedback loop
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Deng, Gongping
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CELL DEATH & DISEASE, 2025, 16 (01):
[14] IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma
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Li, Quan-Lin
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Jiang, Jia-Hao
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Huang, Xiao-Yong
Pan, Jin-Feng
Yan, Jun
Hu, Jin-Hui
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Dai, Zhi
Fan, Jia
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MOLECULAR CANCER, 2011, 10
[15] IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma
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Molecular Cancer, 10
[16] Exosomal circ_0032704 confers sorafenib resistance to hepatocellular carcinoma and contributes to cancer malignant progression by modulating the miR-514a-3p/PD-L1 pathway
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[17] CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress
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[18] METTL3 and METTL14-mediated N6-methyladenosine modification of SREBF2-AS1 facilitates hepatocellular carcinoma progression and sorafenib resistance through DNA demethylation of SREBF2
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[19] METTL3 and METTL14-mediated N6-methyladenosine modification of SREBF2-AS1 facilitates hepatocellular carcinoma progression and sorafenib resistance through DNA demethylation of SREBF2
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