Spontaneous high-frequency action potential

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作者
HaiYing Shen
Wonchae Choe
机构
[1] Kyung Hee University,Department of Biochemistry and Molecular Biology, Medical Research Center and Biomedical Science Institute, School of Medicine
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action potential; spontaneous high-frequency action potential; tachyarrhythmias; atrial fibrillation; wound; denervation supersensitivity; neurogenic pain; hyperalgesia and allodynia; epileptic discharge; diabetic pain; regeneration and development;
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摘要
Action potential, which is the foundation of physiology and electrophysiology, is most vital in physiological research. This work starts by detecting cardiac electrophysiology (tachyarrhythmias), combined with all spontaneous discharge phenomena in vivo such as wound currents and spontaneous neuropathic pain, elaborates from generation, induction, initiation, to all of the features of spontaneous high-frequency action potential—SSL action potential mechanism, i.e., connecting-end hyperpolarization initiates spontaneous depolarization and action potential in somatic membrane. This work resolves the conundrums of in vivo spontaneous discharge in tachyarrhythmias, wounds, denervation supersensitivity, neurogenic pain (hyperalgesia and allodynia), epileptic discharge and diabetic pain in pathophysiological and clinical researches that have puzzled people for a hundred years.
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页码:311 / 335
页数:24
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