Drug-related hepatotoxicity and hepatic failure following combined androgen blockade

被引:0
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作者
Inmaculada Castro Beza
Jesús Sánchez Ruiz
Francisco José Peracaula Espino
M. Isabel Villanego Beltrán
机构
[1] Hospital Punta de Europa,Department of Radiation Oncology
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关键词
Prostate cancer; Hormonal therapy; Nonsteroidal antiandrogen; Drug hepatotoxicity;
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摘要
Androgen deprivation therapy has been the mainstay of treatment for metastatic prostate cancer and of less advanced cancers as neoadjuvant and adjuvant treatment. Abnormal liver function test, in particular elevated transaminases, is an adverse reaction more frequently noticed during androgen deprivation therapy with antiandrogen. We report the case of a patient with acute hepatic failure associated with the use of bicalutamide.
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页码:591 / 592
页数:1
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