Stroke risk in an elderly population with atrial fibrillation

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作者
William M. Feinberg
Richard A. Kronmal
Anne B. Newman
Michael A. Kraut
Edwin G. Bovill
Lawton Cooper
Robert G. Hart
机构
[1] University of Arizona Health Sciences Center,Received from the Department of Neurology
[2] University of Washington,Department of Biostatistics
[3] University of Pittsburgh,Department of Medicine, Division of Geriatric Medicine
[4] Johns Hopkins University,Department of Radiology
[5] University of Vermont,Department of Pathology
[6] National Institutes of Health,National Heart Lung and Blood Institute
[7] University of Texas Health Science Center,Department of Medicine, Neurology Division
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关键词
atrial fibrillation; aged; risk factors; stroke; cerebrovascular disease;
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摘要
Patients with nonvalvular atrial fibrillation (AF) have an increased risk of stroke, but the absolute rate of stroke varies widely depending on coexistent vascular disease. We assessed the stroke rate and predictive value of two published schemes for stroke risk stratification in a population-derived cohort of 259 elderly people with nonvalvular AF followed for a median of 5.3 years. The rate of ischemic stroke was 2.8% per year (95% confidence interval [CI] 1.9, 3.9). Thirty-one percent were predicted to be at low risk, and their stroke rate was 1.7% per year (95% CI 0.6, 3.8). Many people with AF in this population-derived cohort had relatively low rates of stroke. Further studies to reliably stratify stroke risk in patients with AF are needed.
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页码:56 / 59
页数:3
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