Global IRS-1 phosphorylation analysis in insulin resistance

被引:0
|
作者
P. Langlais
Z. Yi
J. Finlayson
M. Luo
R. Mapes
E. De Filippis
C. Meyer
E. Plummer
P. Tongchinsub
M. Mattern
L. J. Mandarino
机构
[1] Arizona State University,Center for Metabolic and Vascular Biology, School of Life Science
[2] Wayne State University,Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy/Health Sciences
[3] Carl T. Hayden VA Medical Center,Division of Endocrinology
[4] Mayo Clinic in Arizona,Department of Medicine
[5] Mayo Clinic in Arizona,undefined
来源
Diabetologia | 2011年 / 54卷
关键词
Insulin resistance; IRS-1; Mass spectrometry; Serine; Phosphorylation; Threonine; Type 2 diabetes;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:2878 / 2889
页数:11
相关论文
共 50 条
  • [41] Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers
    Midori Honma
    Shojiro Sawada
    Yoshiyuki Ueno
    Keigo Murakami
    Tetsuya Yamada
    Junhong Gao
    Shinjiro Kodama
    Tomohito Izumi
    Kei Takahashi
    Sohei Tsukita
    Kenji Uno
    Junta Imai
    Eiji Kakazu
    Yasuteru Kondo
    Kei Mizuno
    Naoki Kawagishi
    Tooru Shimosegawa
    Hideki Katagiri
    International Journal of Obesity, 2018, 42 : 1544 - 1555
  • [42] Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers
    Honma, Midori
    Sawada, Shojiro
    Ueno, Yoshiyuki
    Murakami, Keigo
    Yamada, Tetsuya
    Gao, Junhong
    Kodama, Shinjiro
    Izumi, Tomohito
    Takahashi, Kei
    Tsukita, Sohei
    Uno, Kenji
    Imai, Junta
    Kakazu, Eiji
    Kondo, Yasuteru
    Mizuno, Kei
    Kawagishi, Naoki
    Shimosegawa, Tooru
    Katagiri, Hideki
    INTERNATIONAL JOURNAL OF OBESITY, 2018, 42 (09) : 1544 - 1555
  • [43] Pathogenic role of associated mutations of IRS-1 and insulin receptor (IR) in insulin resistance.
    Macari, F
    Rouard, M
    Bouix, O
    Brun, JF
    Renard, E
    Bringer, J
    Oliver, C
    Jaffiol, C
    Grigorescu, F
    DIABETES, 1997, 46 : 1346 - 1346
  • [44] Dual knockdown of IRS-1 and IRS-2 in liver exacerbates insulin resistance to cause diabetes
    Taniguchi, CM
    Ueki, K
    Kahn, CR
    DIABETES, 2005, 54 : A340 - A341
  • [45] Genetic variants of insulin receptor substrate-1 (IRS-1) in syndromes of severe insulin resistance. Functional analysis of Ala513Pro and Gly1158Glu IRS-1
    Berger, D
    Barroso, I
    Soos, M
    Yeo, G
    Schafer, AJ
    O'Rahilly, S
    Whitehead, JP
    DIABETIC MEDICINE, 2002, 19 (10) : 804 - 809
  • [46] Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function (vol 274, pg 28816, 1999)
    Paz, K
    Liu, YF
    Shorer, H
    Hemi, R
    LeRoith, D
    Quon, MJ
    Kanety, H
    Seger, R
    Zick, Y
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (45) : 32528 - 32528
  • [47] Characterization of IRS-1 Phosphorylation in Type 2 Diabetes
    Langlais, Paul
    Yi, Zhengping
    Finlayson, Jean
    Luo, Moulun
    Mapes, Rebekka
    De Filippis, Eleanna A.
    Meyer, Christian
    Plummer, Elena
    Mattern, Mark J.
    Mandarino, Lawrence J.
    DIABETES, 2010, 59 : A119 - A119
  • [48] Phosphorylation of IRS proteins, insulin action, and insulin resistance
    Boura-Halfon, Sigalit
    Zick, Yehiel
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2009, 296 (04): : E581 - E591
  • [49] Regulation of IRS-1 abilities to transmit insulin signals by the mTOR-dependent IRS-1 translocation
    Kawahara, J
    Haruta, T
    Hiratani, K
    Takano, A
    Uno, T
    Iwata, M
    Usui, I
    Kobayashi, M
    DIABETES, 2004, 53 : A311 - A311
  • [50] Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligation and puncture in mice
    Mathew, Deepa
    Barillas-Cerritos, Julia
    Nedeljkovic-Kurepa, Ana
    Abraham, Mabel
    Taylor, Matthew D.
    Deutschman, Clifford S.
    MOLECULAR MEDICINE, 2023, 29 (01)