UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

被引：0
|
作者：
You-Me Kim
Melanie M. Brinkmann
Marie-Eve Paquet
Hidde L. Ploegh
机构：
[1] Whitehead Institute for Biomedical Research,
[2] 9 Cambridge Center,undefined
[3] Cambridge,undefined
[4] Massachusetts 02142,undefined
[5] USA,undefined
来源：
Nature | 2008年 / 452卷
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摘要：
The membrane protein UNC93B interacts with intracellular Toll-like receptors TLR7 and TLR9. This paper shows that UNC93B specifically controls TLR trafficking from the endoplasmic reticulum to the endolysosome but is not required for ligand recognition or signal initiation.
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页码：234 / 238
页数：4
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