Sonochemical synthesis of pyrido[2,3-d:6,5-d′]-dipyrimidines catalyzed by [HNMP]+[HSO4]− and their antimicrobial activity studies

被引：0
|
作者：
Hossein Naeimi
Asieh Didar
Zahra Rashid
Zohreh Zahraie
机构：
[1] Faculty of Chemistry,Department of Organic Chemistry
[2] University of Kashan,Department of Biotechnology
[3] Young Researchers and Elite Club,undefined
[4] Central Branch,undefined
[5] Islamic Azad University,undefined
[6] Faculty of Chemistry,undefined
[7] University of Kashan,undefined
来源：
The Journal of Antibiotics | 2017年 / 70卷
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摘要：
In this study, the one-pot four-component reaction of aromatic aldehyde, 2-thiobarbituric acid, ammonium acetate in the presence of a catalytic amount of [H-NMP]+[HSO4]− under ultrasonic irradiation in water is reported. In the present procedure, the pyrido[2,3-d:6,5-d′]dipyrimidine derivatives were purely produced as valuable products. The process proved to be simple, environmentally friendly, efficient and high to excellent yielding. Moreover, some of the synthetic compounds were investigated and revealed important antimicrobial activity of prepared products.
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页码：845 / 852
页数：7
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