Reactions of 1-substituted benzo[4,5]imidazo[1,2-a]pyridines

被引：0
|
作者：
Volovenko Yu.M. [1 ]
Ivanov V.V. [1 ]
Pushechnikov A.O. [1 ]
机构：
[1] Taras Shevchenko National University
来源：
Chemistry of Heterocyclic Compounds | 2002年 / 38卷 / 02期
关键词：
Acylation; Benzo[4,5]imidazo[1,2-a]pyridine; Bromination;
D O I：
10.1023/A:1015347527403
中图分类号：
学科分类号：
摘要：
Bromination of 1-oxo(imino, amino)benzo [4,5]imidazo[1,2-a] pyridines gave the corresponding 2-bromo derivatives. Acylation using the Vilsmeier complex in acetic anhydride gave the N-formyl and N-acetyl derivatives. The reaction of the amine with the Vilsmeie1r complex, acetyl acetone, ethyl acetoacetate, and 2,5-dimethoxytetrahydrofuran occurs at the amino group.
引用
收藏
页码：213 / 218
页数：5
相关论文
共 50 条
  • [31] Intramolecular Ullmann-type C-N coupling for the synthesis of substituted benzo[4,5]imidazo[1,2-a]pyrrolo[3,4-c]pyridines
    Maity, Pampa
    Mukhopadhyay, Chhanda
    TETRAHEDRON, 2019, 75 (35)
  • [32] An Efficient Synthesis of Pyrrolo[1,2-a] or Pyrido[1,2-a]benzo[4,5]imidazo[1,2-c]quinazoline Derivatives in Ionic Liquids Catalyzed by Iodine
    Wang, Yue
    Liu, Jian-Quan
    Wang, Xiang-Shan
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2017, 54 (06) : 3440 - 3446
  • [33] Enantioselective Hydrogenation of Imidazo[1,2-a]pyridines
    Schlepphorst, Christoph
    Wiesenfeldt, Mario P.
    Glorius, Frank
    CHEMISTRY-A EUROPEAN JOURNAL, 2018, 24 (02) : 356 - 359
  • [34] Regioselective synthesis of pyrrolo[1,2-a]-imidazoles and imidazo[1,2-a]-pyridines
    Wang, Kai-Min
    Ma, Yu-Lu
    Lin, Xin-Rong
    Yan, Sheng-Jiao
    Lin, Jun
    RSC ADVANCES, 2015, 5 (46): : 36472 - 36479
  • [35] Copper-Catalyzed Intermolecular Oxidative Cyclization of Haloalkynes: Synthesis of 2-Halo-substituted Imidazo[1,2-a]pyridines, Imidazo[1,2-a]pyrazines and Imidazo[1,2-a]pyrimidines
    Gao, Yang
    Yin, Meizhou
    Wu, Wanqing
    Huang, Huawen
    Jiang, Huanfeng
    ADVANCED SYNTHESIS & CATALYSIS, 2013, 355 (11-12) : 2263 - 2273
  • [36] IMIDAZOLE DERIVATIVES .9. SELECTIVE REACTIONS OF FUNCTIONALIZED IMIDAZO[1,2-A]PYRIDINES - STEREOSPECIFIC SYNTHESIS OF 5,6-DIHYDROIMIDAZO[1,2-A]PYRIDINES
    KNOLKER, HJ
    HITZEMANN, R
    TETRAHEDRON LETTERS, 1994, 35 (14) : 2157 - 2160
  • [37] 2-Trifluoromethyl-10H-benzo[4,5]imidazo[1,2-a] pyrimidin-4-one
    Chandra
    Puttaraju, K. B.
    Shivashankar, K.
    Babu, E. A. Jithesh
    Mahendra, M.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O1536 - +
  • [38] One-pot Synthesis of Benzo[4,5]imidazo[1,2-a]pyridine Derivatives in Aqueous Conditions
    Vodolazhenko, Maria A.
    Mykhailenko, Anastasiia E.
    Gorobets, Nikolay Yu.
    Desenko, Sergey M.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2017, 54 (01) : 753 - 757
  • [39] CU(II) BINDING BY 8-SUBSTITUTED-IMIDAZO[1,2-A]PYRIDINES
    DECOCK, P
    DUBOIS, B
    BLONDEAU, D
    SLIWA, H
    KOZLOWSKI, H
    JOURNAL OF COORDINATION CHEMISTRY, 1989, 20 (01) : 1 - 10
  • [40] ANTIULCER AGENTS .3. STRUCTURE ACTIVITY TOXICITY RELATIONSHIPS OF SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND A RELATED IMIDAZO[1,2-A]PYRAZINE
    KAMINSKI, JJ
    PERKINS, DG
    FRANTZ, JD
    SOLOMON, DM
    ELLIOTT, AJ
    CHIU, PJS
    LONG, JF
    JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (11) : 2047 - 2051
12345