Genetic variation in human NPY expression affects stress response and emotion

被引：0

作者：

Zhifeng Zhou

Guanshan Zhu

Ahmad R. Hariri

Mary-Anne Enoch

David Scott

Rajita Sinha

Matti Virkkunen

Deborah C. Mash

Robert H. Lipsky

Xian-Zhang Hu

Colin A. Hodgkinson

Ke Xu

Beata Buzas

Qiaoping Yuan

Pei-Hong Shen

Robert E. Ferrell

Stephen B. Manuck

Sarah M. Brown

Richard L. Hauger

Christian S. Stohler

Jon-Kar Zubieta

David Goldman

机构：

[1] Laboratory of Neurogenetics,Departments of Psychiatry

[2] NIAAA,Departments of Psychiatry and Radiology

[3] NIH,Department of Psychiatry

[4] Bethesda,Department of Psychiatry

[5] Maryland 20892,Department of Neurology

[6] USA ,Department of Psychiatry

[7] Human Genetics,undefined

[8] and Psychology,undefined

[9] University of Pittsburgh,undefined

[10] Pittsburgh,undefined

[11] Pennsylvania 15261,undefined

[12] USA,undefined

[13] University of Michigan Medical School,undefined

[14] Ann Arbor,undefined

[15] Michigan 48109,undefined

[16] USA,undefined

[17] Yale University School of Medicine,undefined

[18] New Haven,undefined

[19] Connecticut 06510,undefined

[20] USA,undefined

[21] University of Helsinki,undefined

[22] 00014,undefined

[23] Helsinki,undefined

[24] Finland,undefined

[25] University of Miami School of Medicine,undefined

[26] Miami,undefined

[27] Florida 33124,undefined

[28] USA,undefined

[29] San Diego VA Healthcare System and University of California,undefined

[30] San Diego,undefined

[31] California 92161,undefined

[32] USA,undefined

[33] School of Dentistry,undefined

[34] University of Maryland,undefined

[35] Baltimore,undefined

[36] Maryland 21201,undefined

[37] USA ,undefined

[38] Present address: Innovation Centre China,undefined

[39] AstraZeneca Global R&D,undefined

[40] Shanghai 201203,undefined

[41] China.,undefined

来源：

Nature | 2008年 / 452卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

An individual's ability to deal with stress and anxiety — risk factors for many diseases — varies widely across human populations and the factors contributing to emotional resilience are complex. A study led by researchers at the National Institute on Alcohol Abuse and Alcoholism now points to inherited variations in the expression of the natural anxiolytic peptide neuropeptide Y in the brain as a factor in determining why some people can withstand stress better than others.

引用

页码：997 / 1001

页数：4

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