Synthesis and antiparasitic activity of N-benzyl cytisine derivatives

被引：0
|
作者：
Sh. B. Rakhimov
Zh. I. Islamova
V. I. Vinogradova
Z. A. Khushbaktova
S. O. Osipova
V. N. Syrov
机构：
[1] Academy of Sciences of the Republic of Uzbekistan,S. Yu. Yunusov Institute of the Chemistry of Plant Substances
[2] Ministry of Health,Republic Scientific Center of Mycology and Protozoan Diseases
[3] Republic of Uzbekistan,undefined
来源：
Pharmaceutical Chemistry Journal | 2013年 / 47卷
关键词：
-benzyl cytisine derivatives; 3-bromocytisine; antiparasitic activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The antiparasitic (antihymenolepiatic and antileishmaniatic) activity of several N-benzyl derivatives of the alkaloid cytisine and 3-bromocytisine was studied. The structure–activity relationship in the series of synthesized compounds was analyzed. It was established that their activity depended on the presence and location of the halide atom in the molecular structure to a greater extent than the on presence of hydroxy or methoxy groups.
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页码：209 / 212
页数：3
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