Neurogenic–angiogenic synchrony via lactate

被引：0
|
作者：
Daniel Z. Doyle
Kenneth Y. Kwan
机构：
[1] University of Michigan,Michigan Neuroscience Institute (MNI)
[2] University of Michigan,Department of Human Genetics
[3] University of Michigan,Neuroscience Graduate Program
来源：
Nature Neuroscience | 2022年 / 25卷
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学科分类号：
摘要：
During cortical development, the generation of neurons from progenitors coincides with increasing vascularization and oxygen levels in the fetal brain and the transition from anaerobic to aerobic metabolism. Dong et al. identify lactate, a metabolite of anaerobic glycolysis, as a multifunctional regulator that coordinates synchrony of cortical neurogenesis and angiogenesis.
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页码：839 / 840
页数：1
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