Hepatitis C virus core protein modulates pRb2/p130 expression in human hepatocellular carcinoma cell lines through promoter methylation

被引：0
|
作者：
Anna Maria Mileo
Stefano Mattarocci
Paola Matarrese
Simona Anticoli
Claudia Abbruzzese
Stefania Catone
Rodolfo Sacco
Marco G. Paggi
Anna Ruggieri
机构：
[1] “Regina Elena” National Cancer Institute,Experimental Oncology
[2] IRCCS,Department of Molecular Biology
[3] University of Geneva,Department of Therapeutic Research and Medicines Evaluation
[4] Istituto Superiore di Sanità,National AIDS Center
[5] Istituto Superiore di Sanità,Gastroenterology and Metabolic Diseases, Department of Gastroenterology
[6] 56124 Pisa University Hospital,Department of Veterinary Public Health & Food Safety
[7] Istituto Superiore di Sanità,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 34卷
关键词：
Hepatitis C Virus; Hepatocellular carcinoma; HCV core protein; pRb2/p130; Cell cycle; Viral oncogenesis; Cell transformation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Effect of hepatitis C virus core shadow protein expressed in human hepatoma cell line on human gene expression profiles
    Dou, Jun
    Liu, Pengbo
    Wang, Jing
    Zhang, Xinjian
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2006, 21 (12) : 1794 - 1800
  • [42] Hepatitis C virus core protein overcomes H2O2-induced apoptosis by downregulating p14 expression via DNA methylation
    Seo, Young Lan
    Heo, Shinhee
    Jang, Kyung Lib
    JOURNAL OF GENERAL VIROLOGY, 2015, 96 : 822 - 832
  • [43] Specific mutations in enhancer II/core promoter of hepatitis B virus subgenotypes C1/C2 increase the risk of hepatocellular carcinoma
    Tanaka, Yasuhito
    Mukaide, Motokazu
    Orito, Etsuro
    Yuen, Man-Fung
    Ito, Kiyoaki
    Kurbanov, Fuat
    Sugauchi, Fuminaka
    Asahina, Yasuhiro
    Izumi, Namiki
    Kato, Michio
    Lai, Ching-Lung
    Ueda, Ryuzo
    Mizokami, Masashi
    JOURNAL OF HEPATOLOGY, 2006, 45 (05) : 646 - 653
  • [44] Nuclear localisation of hepatitis C virus (HCV) NS2 protein in human epithelial cell lines
    von dem Bussche, A
    Söhne, J
    Sauerbruch, T
    Speneler, U
    Dumoulin, FL
    JOURNAL OF HEPATOLOGY, 2000, 32 : 95 - 95
  • [45] Specific Mutations in the Enhancer II/Core Promoter/Precore Regions of Hepatitis B Virus Subgenotype C2 in Korean Patients With Hepatocellular Carcinoma
    Kim, Ja Kyung
    Chang, Hye Young
    Lee, Jung Min
    Baatarkhuu, Oidov
    Yoon, Young Joon
    Park, Jun Yong
    Kim, Do Young
    Han, Kwang-Hyub
    Chon, Chae Yoon
    Ahn, Sang Hoon
    JOURNAL OF MEDICAL VIROLOGY, 2009, 81 (06) : 1002 - 1008
  • [46] Comparison between cytomegalovirus promoter and elongation factor-1 alpha promoter-driven constructs in the establishment of cell lines expressing hepatitis C virus core protein
    Tokushige, K
    Moradpour, D
    Wakita, T
    Geissler, M
    Hayashi, N
    Wands, JR
    JOURNAL OF VIROLOGICAL METHODS, 1997, 64 (01) : 73 - 80
  • [47] Characterization of the effects of hepatitis C virus nonstructural 5A protein expression in human cell lines and on interferon-sensitive virus replication
    Polyak, SJ
    Paschal, DM
    McArdle, S
    Gale, MJ
    Moradpour, D
    Gretch, DR
    HEPATOLOGY, 1999, 29 (04) : 1262 - 1271
  • [48] Hepatitis C virus core protein enhances hepatocellular carcinoma cells to be susceptible to oncolytic vesicular stomatitis virus through down-regulation of HDAC4
    Moon, Jeong
    Kaowinn, Sirichat
    Cho, Il-Rae
    Min, Do Sik
    Myung, Heejoon
    Oh, Sangtaek
    Kaewpiboon, Chutima
    Kraemer, Olive H.
    Chung, Young-Hwa
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 474 (03) : 428 - 434
  • [49] Fusaric acid decreases p53 expression by altering promoter methylation and m6A RNA methylation in human hepatocellular carcinoma (HepG2) cells
    Ghazi, Terisha
    Nagiah, Savania
    Chuturgoon, Anil A.
    EPIGENETICS, 2021, 16 (01) : 79 - 91
  • [50] Inhibition of sirtuins 1 and 2 impairs cell survival and migration and modulates the expression of P-glycoprotein and MRP3 in hepatocellular carcinoma cell lines
    Paula Ceballos, Maria
    Decandido, Giulia
    Dario Quiroga, Ariel
    Gabriela Comanzo, Carla
    Ines Livore, Veronica
    Lorenzetti, Florencia
    Lambertucci, Flavia
    Chazarreta-Cifre, Lorena
    Banchio, Claudia
    de Lujan Alvarez, Maria
    Domingo Mottino, Aldo
    Cristina Carrillo, Maria
    TOXICOLOGY LETTERS, 2018, 289 : 63 - 74
12345